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Supplement Guide Disclaimer
The information presented in Supplement Guide is for informational purposes only and should not be considered medical advice. Nutritional recommendations are based on established guidelines for people of average health and on associations between vitamins, minerals, and herbs with health conditions from published scientific studies (human, animal, or in vitro), clinical experience, or traditional usage. These associations may not be true for all individuals and are not based on specific product brands or formulations. Nutritional and herbal products may vary widely in ingredient purity, concentration, and combinations, which may affect people differently. Consult your doctor, pharmacist, or other professional for any health problem and before adding supplements to your self-care practices or discontinuing any prescribed medications. It is important not to make any changes in your self-care, including taking supplements, before or after a surgery without your doctor's express recommendation. In addition, please consult with your healthcare practitioner to make sure that your cumulative daily intake of copper, selenium, zinc, vitamin B6, folic acid, or any other nutrient, does not exceed established, tolerable upper intake levels.
Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.
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- Vitamins & Supplements
- Melatonin
Melatonin for a Good Night’s Sleep


Melatonin Promotes a Restful Sleep for Health
Life Extension® helps you get healthy restful sleep with our variety of melatonin products. Melatonin is a hormone made naturally by our bodies — but those who have trouble sleeping may not be producing enough of it at the right time. Life Extension® helps you get healthy restful sleep with our variety of melatonin products.
4 Reasons Why Everyone Should Take Our Melatonin Supplements
- Promotes healthy, restful sleep
- Helps balance circadian rhythm and immune function
- Protects cellular DNA by inhibiting oxidative stress and free radicals
- Available as time-released, fast-acting and multiple dosages
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Our Recommendation
Compare Formulations
At Life Extension®, we understand that each of us have different needs, especially when it comes to sleep. Discover the variety of melatonin supplements available and learn which is best to fit your needs.

Immediate Release
Not everyone reacts the same to melatonin supplements. Some need stronger doses, while others require smaller amounts of this sleep promoting hormone. To provide you with the right melatonin supplement, we offer a variety of dosages and formulations. So no matter your needs, you’ll rest easy.
See Melatonin Immediate Release Products
Extended Release
We all have different needs, especially when it comes to sleep. For some staying asleep is an issue. And that‘s why we offer time-released melatonin products. These formulations slowly release melatonin, to help you have a sustained, restful sleep—all night long.
See Melatonin Extended Release Products
Melatonin with added ingredients
Melatonin also has strong antioxidant properties which help the body beyond helping regulate sleep patterns. To boost these properties even further, we’ve formulated our melatonin supplements with vitamins and minerals that help reduce stress, provide antioxidant protection and more.
See Melatonin with added ingredients ProductsImmediate Release
Everyone reacts to melatonin differently. That’s why we offer doses that range from as low as 500 mcg up to 10 mg of this sleep promoting hormone. So whether you need a little or a lot, we have the perfect dose to help you get the rest you need for better health.
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Our melatonin supplements help support circadian rhythms, healthy and restful sleep, immune health and more while helping to inhibit oxidative stress.
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Our melatonin supplements help support circadian rhythms, healthy and restful sleep, immune health and more while helping to inhibit oxidative stress.
- Save
Wholesale
- Select Multi-Unit Discount
Our melatonin supplements help support circadian rhythms, healthy and restful sleep, immune health and more while helping to inhibit oxidative stress.
- Save
Wholesale
- Select Multi-Unit Discount
Our melatonin supplements help support circadian rhythms, healthy and restful sleep, immune health and more while helping to inhibit oxidative stress.
- Save
Wholesale
- Select Multi-Unit Discount
Our melatonin supplements help support circadian rhythms, healthy and restful sleep, immune health and more while helping to inhibit oxidative stress.
- Save
Wholesale
- Select Multi-Unit Discount
Our melatonin supplements help support circadian rhythms, healthy and restful sleep, immune health and more while helping to inhibit oxidative stress.
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- Select Multi-Unit Discount
Not everyone benefits from taking melatonin capsules or tablets. Our Fast-Acting Liquid Melatonin supports optimal sleep and well-being with a completely sugar-free and delicious citrus-vanilla flavor.
Extended Release
Melatonin IR/XR contains an innovative 50/50 blend of immediate- and extended-release melatonin to help you fall asleep quickly and stay asleep all night long. For those who are able to fall asleep, but aren’t able to stay asleep all night, Melatonin 6 Hour formula gradually releases melatonin to help you get a restful healthy sleep.
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Melatonin IR/XR helps you fall asleep and stay asleep all night long by combining immediate-release and extended-release melatonin for approximately seven hours of healthy sleep support.
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Melatonin is known to help you fall asleep. Our formula releases 300 mcg of melatonin over a period of six hours to help you fall asleep and stay asleep.
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Melatonin is known to help you fall asleep. Our formula releases 750 mcg of melatonin over a period of six hours to help you fall asleep and stay asleep.
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Melatonin is known to help you fall asleep. Our formula releases 3 mg of melatonin over a period of six hours to help you fall asleep and stay asleep.
Melatonin with added ingredients
To help boost melatonin’s sleep inducing properties, we augmented some of our formulations with additional ingredients to promote relaxation, regulate sleep-wake cycles and help maintain whole-body health.
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By supporting both central and peripheral circadian clocks, our Circadian Sleep represents an innovative, restorative approach to promoting healthy circadian rhythms, resulting in multiple benefits for whole-body health.
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Our Enhanced Sleep with Melatonin delivers three clinically studied compounds that encourage restful sleep, a healthy response to stress, youthful-looking skin and other benefits.
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Quiet Sleep Melatonin is a comprehensive sleep-support supplement. It combines 5 mg of immediate-release melatonin with vitamin C, B12, inositol and more to promote healthy sleep.
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Quiet Sleep is a comprehensive sleep support supplement. It combines 3 mg of immediate-release melatonin with vitamin C, B12, inositol and more to promote healthy sleep.
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Our Once-Daily Health Booster delivers the health benefits of essential fat-soluble vitamins and nutrients from plant extracts and a phospholipid blend for eye health, all contained in one convenient softgel.
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PQQ’s benefits stem from our special formula, which is designed to promote healthy mitochondria, the cellular structures that produce energy needed by the entire body.
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Our best-selling Super Omega-3 EPA/DHA formula is an IFOS™ 5-star certified fish oil packed with EPA and DHA fatty acids, olive polyphenols and more to promote heart health, brain health, and beyond.
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Nutrients like lutein and astaxanthin benefit eye health. Our MacuGuard® formula delivers these nutrients, plus zeaxanthin, meso-zeaxanthin, saffron and more for comprehensive eye health support.
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Our PQQ (pyrroloquinoline quinone) supplement is a powerful antioxidant that supports the growth of brand-new mitochondria, to support cellular energy.
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We’ve augmented our ultra-bioavailable Curcumin Elite™ curcumin-fenugreek combo with complementary ginger and turmerone extracts to create our Best in Class curcumin formula.
Related Health Information
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